PLX-4545 [2892065-45-9]

TargetMol Chemicals

PLX-4545 [2892065-45-9]

9

Research Use Only

C28H31N3O4

473.56

PLX-4545 has oral biological activity and is a cereblon based IKZF2 (zinc finger transcription factor Helios) molecular gel degrading agent that acts on immune suppressive regulatory T cells, reprogramming them into pro-inflammatory effector T cells and enhancing anti-tumor immune response.

O([C@@H]1[C@H](CCCC1)N2CC(C2)C3=CC=CC=C3)C=4C=C5C(=CC4)C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6

-20°C

12352200