PLX5622 hemifumarate
T12505
Molecular Weight453.45
Product group Chemicals
Overview
- SupplierTargetMol Chemicals
- Product NamePLX5622 hemifumarate
- Delivery Days Customer10
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NamePLX5622 hemifumarate
- Molecular FormulaC25H23F2N5O5
- Molecular Weight453.45
- Scientific DescriptionPLX5622 hemifumarate is a highly selective, brain-penetrant, and orally active CSF1R inhibitor with an IC50 of 0.016 microM and Ki of 5.9 nM. It allows for extended and specific microglial elimination preceding and during pathology development and demonstrates desirable PK properties in various animals [1] [2].
- Shelf life instruction3 years
- SMILESCOC1=NC=C(F)C=C1CNC2=NC(F)=C(CC3=CNC4=NC=C(C)C=C43)C=C2.O=C(O)/C=C/C(O)=O.[1/2]
- Storage Instruction-20°C
- UNSPSC12352200