PMAIP1 Antibody, HRP conjugated

Cusabio

PMAIP1 Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

adult T cell leukemia-derived PMA-responsive; APR; immediate-early-response protein APR; NOXA; phorbol-12-myristate-13-acetate-induced protein 1; PMA-induced protein 1; protein Noxa

Rabbit

IgG

Phorbol-12-myristate-13-acetate-induced protein 1

Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1. Competes with BAK1 for binding to MCL1 and can displace BAK1 from its binding site on MCL1 (By similarity). Competes with BIM/BCL2L11 for binding to MCL1 and can displace BIM/BCL2L11 from its binding site on MCL1.

Human

-20°C or -80°C

12352203