PMS2

Biorbyt

PMS2

10

ImmunoHistoChemistry

IHC

Research Use Only

Monoclonal

IHC422

Unconjugated

Rabbit

IgG

Postmeiotic Segregation Increased 2 (PMS2) is a DNA repair protein involved in mismatch repair. Mutations and deficiencies in the PMS2 gene have been linked to microsatellite instability and malignancies such as hereditary nonpolyposis colorectal cancer and endometrial cancer. Expression levels of the PMS2 protein may be useful as a screening tool for Lynch syndrome after a colorectal cancer diagnosis. Anti-PMS2 is recommended to be used as part of a panel along with antibodies against MSH2, MSH6, and MLH1.

Human

2°C to 8°C

12352203