PMS2 Polyclonal Antibody

Reddot Biotech

PMS2 Polyclonal Antibody

5

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

0.3 mg/ml

Unconjugated

PMS2

PMS1 homolog 2, mismatch repair system component

DNA mismatch repair protein PMS2; HNPCC4; mismatch repair endonuclease PMS2; MLH4; MMRCS4; PMS1 homolog 2, mismatch repair protein; PMS1 protein homolog 2; PMS2 postmeiotic segregation increased 2; PMS2CL; PMSL2; postmeiotic segregation increased 2 nirs variant 6

Rabbit

IgG

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene.

Human

-20°C

12352203