PNP Polyclonal Antibody
RD266202A
ApplicationsImmunoFluorescence
Product group Antibodies
ReactivityHuman, Mouse
TargetPNP
Overview
- SupplierReddot Biotech
- Product NamePNP Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID4860
- Target namePNP
- Target descriptionpurine nucleoside phosphorylase
- Target synonymsepididymis secretory sperm binding protein Li 156an; HEL-S-156an; inosine phosphorylase; inosine-guanosine phosphorylase; NP; PRO1837; PUNP; purine nucleoside phosphorylase; purine-nucleoside:orthophosphate ribosyltransferase
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203