PNPLA1 antibody, Internal

GeneTex

PNPLA1 antibody, Internal

9

WB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.5-1 mg/ml

Unconjugated

PNPLA1

patatin like domain 1, omega-hydroxyceramide transacylase

ARCI10, dJ50J22.1, omega-hydroxyceramide transacylase, patatin like phospholipase domain containing 1, patatin-like phospholipase domain-containing protein 1

Rabbit

IgG

Omega-hydroxyceramide transacylase

The protein encoded by this gene belongs to the patatin-like phospholipase (PNPLA) family, which is characterized by the presence of a highly conserved patatin domain. PNPLA family members have diverse lipolytic and acyltransferase activities, and are key elements in lipid metabolism. While other members of this family have been well characterized, the function of this gene remained an enigma. However, recent studies show that this gene is expressed in the skin epidermal keratinocytes, and has a role in glycerophospholipid metabolism in the cutaneous barrier. Consistent with these observations, mutations in this gene are associated with ichthyosis in human (autosomal recessive congenital ichthyoses, ARCI) and dog. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012]

Human

-20°C or -80°C,2°C to 8°C

41116161