PNZ5

MedChem Express

PNZ5 [1629277-36-6]

10

1629277-36-6

Research Use Only

C20H18N2O2

318.37

PNZ5 is a potent and isoxazole-based pan-BET inhibitor with high selectivity and potency similar to the well-established (+)-JQ1, with a K D of 5.43 nM for BRD4(1) [1] .

CN1C(C2=CC=C(C3=C(C)ON=C3C)C=C2[C@@]1(C4=CC=CC=C4)[H])=O

12352200