Podocalyxin Antibody / PODXL

Biorbyt

Podocalyxin Antibody / PODXL

16

ImmunoHistoChemistry

Immunohistochemistry (FFPE): 1-2ug/ml IHC-P

Research Use Only

PODXL/2184

IgG

Podocalyxin is a member of the CD34 transmembrane sialomucin family. It is over-expressed on the podocyte foot projections and plays essential roles in kidney development and homeostasis, blood filtration and urine formation. It is also expressed on vascular endothelia, hematopoietic progenitors and a subset of neurons. Overexpression of podocalyxin may be linked to more aggressive tumor behavior. Podocalyxin antibody can identify podocytes in the urine (podocyturia) that may indicate glomerular disease, pre-eclampsia, and other kidney pathology.

12352203