Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH [2351103-63-2]

TargetMol Chemicals

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH [2351103-63-2]

14

2351103-63-2

Chemical

Research Use Only

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH

C31H44N4O11

648.7

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized E3 ligase ligand-linker conjugate, incorporating the cereblon ligand from Pomalidomide and a linker used in PROTAC technology. It facilitates targeted protein degradation by modulating E3 ligase activity, thereby enabling the selective elimination of specific proteins of interest.

3 years

O=C(O)COCCCCCOCCOCCCCCOCC(=O)NCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3

-20°C

12352200