Pomisartan

MedChem Express

Pomisartan

5

Research Use Only

C31H30N4O2

490.60

Pomisartan is an orally active angiotensin II receptor type AT1 antagonist ( IC 50 =0.26 microM). Pomisartan works by inhibiting the binding of angiotensin II to the AT1 receptor, thereby blocking the vasoconstriction and aldosterone release caused by this interaction. Pomisartan results in a blood pressure-lowering effect [1] .

O=C(C1=C(C2=CC=C(CN3C4=CC(C5=CN(CCCC6)C6=N5)=CC(C)=C4N=C3CC)C=C2)C=CC=C1)O

12352200