POMK Polyclonal Antibody
RD82174A
ApplicationsWestern Blot
Product group Antibodies
ReactivityMouse, Rat
TargetPOMK
Overview
- SupplierReddot Biotech
- Product NamePOMK Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsWestern Blot
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID84197
- Target namePOMK
- Target descriptionprotein O-mannose kinase
- Target synonymsMDDGA12; MDDGC12; probable inactive protein kinase-like protein SgK196; protein kinase-like protein SgK196; protein O-mannose kinase; SGK196; Sugen kinase 196
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThis gene encodes a protein that may be involved in the presentation of the laminin-binding O-linked carbohydrate chain of alpha-dystroglycan (a-DG), which forms transmembrane linkages between the extracellular matrix and the exoskeleton. Some pathogens use this O-linked carbohydrate unit for host entry. Loss of function compound heterozygous mutations in this gene were found in a human patient affected by the Walker-Warburg syndrome (WWS) phenotype. Mice lacking this gene contain misplaced neurons (heterotopia) in some regions of the brain, possibly from defects in neuronal migration. Alternative splicing of this gene results in multiple transcript variants.
- ReactivityMouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203