PPMC [99290-94-5]

TargetMol Chemicals

PPMC [99290-94-5]

72

Chemical

PPMC

C15H21NO

231.33

The alpha-adrenoceptors blocking effect of (N-piperidinomethyl)-2-chromanne was studied in vivo and in vitro in the rat. In the pithed rat, (N-piperidinomethyl)-2-chromanne (1 mg/kg i.v.) antagonized the pressor effects induced by alpha agonists. (N-piperidinomethyl)-2-chromanne competitively antagonized the pressor effects of M7 (alpha 2-agonist) and cirazoline (alpha 1-agonist). (N-piperidinomethyl)-2-chromanne antagonized the inhibitory effects of clonidine on presynaptic alpha 2-receptors in stimulated pithed rats.

3 years

C(C1OC=2C(CC1)=CC=CC2)N3CCCCC3

-20°C

12352200