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PPTN hydrochloride [1992047-65-0]

PPTN hydrochloride [1992047-65-0]

Research Use Only
T63534
TargetMol Chemicals
CAS Number1992047-65-0
DownloadMSDS
Product group Chemicals
Estimated Purity99.94%
Molecular Weight511.96
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    PPTN hydrochloride [1992047-65-0]
  • Delivery Days Customer
    4
  • CAS Number
    1992047-65-0
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    PPTN hydrochloride
  • Estimated Purity
    99.94%
  • Molecular Formula
    C29H25ClF3NO2
  • Molecular Weight
    511.96
  • Scientific Description
    PPTN hydrochloride is a potent, high-affinity, competitive, and highly selective P2Y14 receptor antagonist (KB: 434 pM) with no agonist or antagonist activity at P2Y1, P2Y2, P2Y4, P2Y6, P2Y11, P2Y12, or P2Y13 receptors, exhibiting anti-inflammatory and anti-immune effects.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.OC(=O)c1cc(-c2ccc(cc2)C2CCNCC2)c2ccc(cc2c1)-c1ccc(cc1)C(F)(F)F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain. Lin J et al., 2019 Dec, Neurochem Int
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