PQ-10 [927691-21-2]

MedChem Express

PQ-10 [927691-21-2]

10

927691-21-2

Research Use Only

99.77

C22H21N5O3

403.43

PQ-10 is a potent inhibitor of Phosphodiesterase 10A (PDE10A) with IC50 andED50 of 4.6 nM and 13 mg/kg, respectively. PQ-10 induces patterns of brain glucose metabolism which can be a potential translational biomarker. PQ-10 has the potential for researching psychiatric disorders like schizophrenia[1].

COC1=CC(C(N(CC2)C[C@@H]2OC3=NC(C=CC=C4)=C4N=C3)=NC=N5)=C5C=C1OC

-20°C,2°C to 8°C

12352200