Bio-Connect

PR-104A [680199-06-8]

HY-14572
MedChem Express
Product group Molecular Biology
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PR-104A [680199-06-8]
  • Delivery Days Customer
    10
  • CAS Number
    680199-06-8
  • Certification
    Research Use Only
  • Estimated Purity
    98.98
  • Molecular Formula
    C14H19BrN4O9S
  • Molecular Weight
    499.29
  • Scientific Description
    PR-104A (SN 27858) is the alcohol metabolite of phosphate proagent PR-104. PR-104A is a hypoxia-selective DNA cross-linking agent/DNA-damaging agent and cytotoxin. Antitumor Activity[1]. PR-104A is metabolized under hypoxia by the 1-electron NADPH:cytochrome P450 oxidoreductase. PR-104A can be used for the research of relapsed/refractory T-lineage acute lymphoblastic leukemia (T-ALL)[2].
  • SMILES
    BrCCN(CCOS(=O)(C)=O)C1=C(C(NCCO)=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    41115800