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PRAME Polyclonal Antibody

Research Use Only
RD252200A
Reddot Biotech
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetPRAME
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Overview

  • Supplier
    Reddot Biotech
  • Product Name
    PRAME Polyclonal Antibody
  • Delivery Days Customer
    5
  • Applications
    ELISA, ImmunoHistoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID23532
  • Target name
    PRAME
  • Target description
    PRAME nuclear receptor transcriptional regulator
  • Target synonyms
    cancer/testis antigen 130; CT130; MAPE; melanoma antigen preferentially expressed in tumors; OIP4; OIP-4; opa-interacting protein 4; Opa-interacting protein OIP4; preferentially expressed antigen in melanoma; preferentially expressed antigen of melanoma
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants.
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203