PRDX1-IN-2
HY-158368
Overview
- SupplierMedChem Express
- Product NamePRDX1-IN-2
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC35H48N2O5
- Molecular Weight576.77
- Scientific DescriptionPRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) (IC50=0.35 microM). PRDX1-IN-2 decreases the mitochondria membrane potential of SW620 cells, probably due to ROS induced by PRDX1 inhibition, leading to cell apoptosis. PRDX1-IN-2 can be used for colorectal cancer research[1].
- SMILESO=C1C(O)=C(C2=CC=C3[C@](C)([C@]4(CC[C@]3(C2=C1)C)C)CC[C@@]5([C@]4(C[C@](NC(NC6(C(OC)=O)CCC6)=O)(CC5)C)[H])C)C
- UNSPSC12352200