Bio-Connect

PRDX1-IN-2

HY-158368
MedChem Express
Molecular Weight576.77
Product group Chemicals
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PRDX1-IN-2
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Molecular Formula
    C35H48N2O5
  • Molecular Weight
    576.77
  • Scientific Description
    PRDX1-IN-2 (compound 15) is a selective inhibitor of the antioxidant enzyme Peroxiredoxin 1 (PRDX1) (IC50=0.35 microM). PRDX1-IN-2 decreases the mitochondria membrane potential of SW620 cells, probably due to ROS induced by PRDX1 inhibition, leading to cell apoptosis. PRDX1-IN-2 can be used for colorectal cancer research[1].
  • SMILES
    O=C1C(O)=C(C2=CC=C3[C@](C)([C@]4(CC[C@]3(C2=C1)C)C)CC[C@@]5([C@]4(C[C@](NC(NC6(C(OC)=O)CCC6)=O)(CC5)C)[H])C)C
  • UNSPSC
    12352200