PRDX1-IN-3
HY-171272
Molecular Weight550.73
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePRDX1-IN-3 [2566976-46-1]
- Delivery Days Customer5
- CertificationResearch Use Only
- Molecular FormulaC33H46N2O5
- Molecular Weight550.73
- Scientific DescriptionPRDX1-IN-3 (compound 19-048) is a PRDX1 covalent inhibitor with anti-colorectal cancer activity. PRDX1-IN-3 can effectively inhibit the proliferation of colorectal cancer cells, and its antitumor effect on nude mice with colorectal cancer carrying PRDX1 gene knockout is significantly reduced. PRDX1-IN-3 also upregulates the downstream genes of the p53 signaling pathway to exert an anticancer effect[1].
- SMILESC[C@@]12[C@]([C@@]3([H])[C@@](CC1)(CC[C@](C)(C3)NC(N[C@@H](C)C(OC)=O)=O)C)(CC[C@@]4(C2=CC=C5C4=CC(C(O)=C5C)=O)C)C
- UNSPSC12352200