Prion Protein (PrP) (143-153) blocking peptide
GTX89339-PEP
Product group Proteins / Signaling Molecules
Overview
- SupplierGeneTex
- Product NamePrion Protein (PrP) (143-153) blocking peptide
- Delivery Days Customer9
- CertificationResearch Use Only
- FormulationLyophilized
- Scientific DescriptionThe protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352202
References
- The Effects of Fibrinogens Interactions with Its Neuronal Receptors, Intercellular Adhesion Molecule-1 and Cellular Prion Protein. Sulimai N et al., 2021 Sep 18, BiomoleculesRead more
- Fibrinogen Interaction with Astrocyte ICAM-1 and PrPC Results in the Generation of ROS and Neuronal Death. Sulimai N et al., 2021 Feb 27, Int J Mol SciRead more
- Fibrinogen-cellular prion protein complex formation on astrocytes. Charkviani M et al., 2020 Aug 1, J NeurophysiolRead more