PRKAG1 Polyclonal Antibody
RD84405A
ApplicationsImmunoFluorescence, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPRKAG1
Overview
- SupplierReddot Biotech
- Product NamePRKAG1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsImmunoFluorescence, ImmunoHistoChemistry
- CertificationResearch Use Only
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5571
- Target namePRKAG1
- Target descriptionprotein kinase AMP-activated non-catalytic subunit gamma 1
- Target synonyms5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMPK gamma1; AMPK gamma-1 chain; AMPKG; protein kinase, AMP-activated, gamma 1 non-catalytic subunit
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C
- UNSPSC12352203