PRMT5-IN-45
HY-168263
Molecular Weight473.57
Product group Chemicals
Overview
- SupplierMedChem Express
- Product NamePRMT5-IN-45
- Delivery Days Customer9
- CertificationResearch Use Only
- Molecular FormulaC26H31N7O2
- Molecular Weight473.57
- Scientific DescriptionPRMT5-IN-45 (compound 36) is a potent and selective PRMT5 inhibitor with an IC50 of 3 nM. PRMT5-IN-45 potently reduces the level of symmetric dimethylarginines (sDMA) and inhibits the proliferation of MOLM-13 cell lines by inducing apoptosis and cell cycle arrest[1].
- SMILESO[C@@H]1[C@H](O)[C@@H](CCC2=CC=C3C=CC(N)=NC3=C2)C[C@H]1N4C=CC5=C(N6CCNCC6)N=CN=C54
- UNSPSC12352200