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ProductsBack/Proadifen (hydrochloride) (Standard) [62-68-0]

Proadifen (hydrochloride) (Standard) [62-68-0]

Research Use Only
HY-B1311R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Proadifen (hydrochloride) (Standard)
  • Delivery Days Customer
    9
  • CAS Number
    62-68-0
  • Certification
    Research Use Only
  • Molecular Formula
    C23H32ClNO2
  • Molecular Weight
    389.96
  • Scientific Description
    Proadifen (hydrochloride) (Standard) is the analytical standard of Proadifen (hydrochloride). This product is intended for research and analytical applications. Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 microM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases[1][2][3][4][5][6].
  • SMILES
    O=C(OCCN(CC)CC)C(CCC)(C1=CC=CC=C1)C2=CC=CC=C2.[H]Cl
  • UNSPSC
    41116135