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Chemical Structure
Chemical Structure
Chemical Structure

Prostaglandin E1

CDX-P0450
Chemodex
CAS Number745-65-3
Product group Chemicals
Estimated Purity>98%
Molecular Weight354.49
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Overview

  • Supplier
    Chemodex
  • Product Name
    Prostaglandin E1 [745-65-3]
  • Delivery Days Customer
    10
  • CAS Number
    745-65-3
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger,Excepted quantity
  • Molecular Formula
    C20H34O5
  • Molecular Weight
    354.49
  • Scientific Description
    Chemical. CAS: 745-65-3. Formula: C20H34O5. MW: 354.49. Prostaglandin E1 (PGE1) is an endogenous prostaglandin used as a medication. Its synthetic form, alprostadil, is a vasodilator and smooth muscle relaxant used for several different medical purposes. PGE1 is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival. - Prostaglandin E1 (PGE1) is an endogenous prostaglandin used as a medication. Its synthetic form, alprostadil, is a vasodilator and smooth muscle relaxant used for several different medical purposes. PGE1 is the theoretical cyclooxygenase metabolite of dihomo-gamma-linolenic acid (DGLA), but it is virtually undetectable in the plasma of normal humans or other animals. Its pharmacology includes vasodilation, hypotension and anti-platelet activities. The IC50 of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. The vasorelaxant and anti-hypertensive effects of PGE1 are used to treat male erectile dysfunction and to provide emergency vasodilation of the patent ductus arteriosus in infants whose cardiac anomalies require pulmonary shunting for survival.
  • SMILES
    O[C@@H]([C@H](/C=C/[C@@H](O)CCCCC)[C@H]1CCCCCCC(O)=O)CC1=O
  • Storage Instruction
    -20°C
  • UN Number
    2811
  • UNSPSC
    12352200

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