PROTAC alpha-synuclein degrader 3

MedChem Express

PROTAC alpha-synuclein degrader 3

5

Research Use Only

99.61

C51H68N6O11S2

1005.25

PROTAC alpha-synuclein degrader 3 (Compound 5) is a selective alpha-synuclein PROTAC degrader. PROTAC alpha-synuclein degrader 3 can promote the ubiquitination and degradation of alpha-synuclein. PROTAC alpha-synuclein degrader 3 can be used for Parkinsons disease research (Pink: target protein ligand (HY-W278021); Black: linker; HY-133302; Blue: E3 ligase VHL ligand (HY-112078))[1].

CNC(C=C1)=CC=C1C2=NC3=C(S2)C=C(OCCOCCOCCOCCOCCOCCOCC(N[C@@H](C(C)(C)C)C(N4[C@H](C(N[C@H](C5=CC=C(C6=C(C)N=CS6)C=C5)C)=O)C[C@@H](O)C4)=O)=O)C=C3

2°C to 8°C

12352200