PROTAC alpha-synuclein degrader 6

MedChem Express

PROTAC alpha-synuclein degrader 6

5

Research Use Only

99.28

C37H39N5O9S

729.80

PROTAC alpha-synuclein degrader 6 (compound T3) is a PROTAC degrader of alpha-synuclein and tau, with EC50 of 1.57 microM and 4.09 microM, respectively. PROTAC alpha-synuclein degrader 6 plays an important role in neurodegenerative diseases (NDs) research (Blue:ubiquitin E3 ligase cereblon ligand (HY-14658), Black: linker (HY-128803); Pink: Ligand for target protein (HY-151035))[1].

O=C(N1C2C(NC(CC2)=O)=O)C3=CC=CC(OCC(NCCOCCOCCOCCNC4=CC=C(C(S5)=NC6=C5C=C(C)C=C6)C=C4)=O)=C3C1=O

-20°C,2°C to 8°C

12352200