PROTAC AR Degrader-5 [2703021-51-4]

TargetMol Chemicals

PROTAC AR Degrader-5 [2703021-51-4]

16

Research Use Only

C52H54F4N8O7S2

1043.16

PROTAC AR Degrader-5 (compound A46) is a powerful AR PROTAC Degrader exhibiting an IC 50 of 49 nM. It not only inhibits sebaceous plaque but also promotes hair regeneration [1].

S=C1N(C(=O)C(C)(C)N1C=2C=CC(=NC2)C3=CC=C(OCCCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](O)C4)C(C)(C)C)=O)C=C3)C7=C(F)C(C(F)(F)F)=C(C#N)C=C7

-20°C

51202000