PROTAC BcI-2/BcI-xI Degrader-1

MedChem Express

PROTAC BcI-2/BcI-xI Degrader-1

5

Research Use Only

C78H94ClF3N10O12S4

1584.35

PROTAC BcI-2/BcI-xI Degrader-1 (15) is a PROTAC based BcI-2/BcI-xI degrader (Red: BcI-2/BcI-xI inhibitor (HY-158677), black: linker, Blue: E3 ligase ligand)[1].

O=S(NC(C1=CC=C(N2[C@@](CO3)([H])CN(CC2)CC4=C(C5=CC=C(C=C5)Cl)CCC(C)(C4)C)C3=C1)=O)(C6=CC(S(C(F)(F)F)(=O)=O)=C(C=C6)N[C@@H](CSC7=CC=CC=C7)CCN8CCN(CC8)C(CCCCCC(N[C@@H](C(C)(C)C)C(N9[C@@H](C[C@H](C9)O)C(NCC%10=CC=C(C%11=C(N=CS%11)CCO%12)C%12=C%10)=O)=O)=O)=O)=O

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