PROTAC BRD4-DCAF1 degrader-1

MedChem Express

PROTAC BRD4-DCAF1 degrader-1

9

Research Use Only

C60H64Cl2F2N8O9S

1182.17

PROTAC BRD4-DCAF1 degrader-1 (I-907) is a BRD4-DCAF1 PROTAC degrader, DC50 is 10~100 nM. (Pink: BRD4-DCAF1 ligand (HY-169152); Black: linker (HY-126976); Blue: E3 ligase ligand (HY-15846))[1].

CC1=C(C)SC2=C1C(C3=CC=C(C=C3)Cl)=N[C@@H](CC(NCCOCCOCCOCCOCCOCCCC4=CC=C(C=C4)C(C5=C(C6=C(C(F)=CC=C6F)C)C(C(N[C@H](C7=CC(Cl)=CC=C7)CC(N)=O)=O)=CN5)=O)=O)C8=NN=C(C)N28

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