PROTAC CDK12/13 Degrader-1 (TFA)

MedChem Express

PROTAC CDK12/13 Degrader-1 (TFA)

10

Research Use Only

98.37

C47H47F3N10O8

936.93

PROTAC CDK12/13 Degrader-1 (7f) TFA is a highly selective cell cycle protein-dependent kinase CDK12/CDK13 dual degrader with the DC 50 values of 2.2 nM and 2.1 nM, respectively. PROTAC CDK12/13 Degrader-1 TFA has anti-proliferative activity and can be used in breast cancer research [1] .

O=C(NCC1=CC=CC=C1)N([C@H]2CC[C@H](NC3=NC=C(C#N)C=C3)CC2)C4=CC=C(N5CCN(C(CNC6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7=O)=O)C=C6)=O)CC5)C=C4.O=C(O)C(F)(F)F

-20°C

12352200