Bio-Connect

PROTAC EED degrader-1

HY-130614
MedChem Express
CAS Number2639882-72-5
Product group Chemicals
Estimated Purity98.27
Molecular Weight1054.20
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Overview

  • Supplier
    MedChem Express
  • Product Name
    PROTAC EED degrader-1 [2639882-72-5]
  • Delivery Days Customer
    5
  • CAS Number
    2639882-72-5
  • Certification
    Research Use Only
  • Estimated Purity
    98.27
  • Molecular Formula
    C55H60FN11O8S
  • Molecular Weight
    1054.20
  • Scientific Description
    PROTAC EED degrader-1 is a von Hippel-Lindau -based PROTAC targeting EED with a pK D of 9.02. PROTAC EED degrader-1 is a polycomb repressive complex 2 ( PRC2 ) inhibitor ( pIC 50 =8.17) targeting the EED subunit [1] .
  • SMILES
    FC1=CC=C2C(CCO2)=C1CNC3=NC=C(C4=C(C)N=C(CCC(NCCOC5=CC=C(OCC(N[C@@H](C(C)(C)C)C(N6[C@H](C(NCC7=CC=C(C8=C(C)N=CS8)C=C7)=O)C[C@@H](O)C6)=O)=O)C=C5)=O)C=C4)C9=NN=CN39
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200