PROTAC EGFR degrader 3 [2768472-28-0]

TargetMol Chemicals

PROTAC EGFR degrader 3 [2768472-28-0]

999

Chemical

Research Use Only

PROTAC EGFR degrader 3

C60H77N13O5S

1092.4

PROTAC EGFR Degrader 3, a highly potent molecule, exhibits remarkable cellular activity against H1975 and HCC827 cells, maintaining high selectivity. It additionally reveals the lysosomes crucial role in the degradation mechanism of mutant EGFR [1].

3 years

C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCN1CCN(CC1)c1ccc(Nc2ncc3nc(Nc4ccccc4)n([C@H]4CCCN(C4)C(=O)C=C)c3n2)cc1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

-20°C

51202000