PROTAC EGFR degrader 6 [2409793-28-6]

TargetMol Chemicals

PROTAC EGFR degrader 6 [2409793-28-6]

999

Chemical

Research Use Only

PROTAC EGFR degrader 6

C49H57FN12O5

913.05

PROTAC EGFR degrader 6 is a potent PROTAC EGFR degrader that effectively reduces EGFR Del19 levels in HCC827 cells, exhibiting a DC50 of 45.2 nM. It notably promotes apoptosis and induces G1 phase arrest in HCC827 cells [1].

3 years

OCC1CCN(CC1)c1nc(Nc2ccc(F)cc2)nc2cnc(Nc3ccc(cn3)N3CCN(CCCCCCCC(=O)Nc4cccc5C(=O)N(Cc45)C4CCC(=O)NC4=O)CC3)cc12

-20°C

51202000