PROTAC ERalpha Degrader-7 [3025781-93-2]

TargetMol Chemicals

PROTAC ERalpha Degrader-7 [3025781-93-2]

16

Research Use Only

C46H49F2N5O4

773.91

PROTAC ERalpha Degrader-7 (Compound i-320) is a powerful PROTAC degrader targeting the estrogen receptor alpha (ERalpha), exhibiting a DC50 of 0.000006 microM. This compound consists of a cereblon-binding segment, LBM, connected to ERBM, an ERalpha-binding ligand that includes a benzofused partially saturated 6-membered carbocyclic or heterocyclic ring [1].

FC1(F)C[C@@H]([C@@H](C=2C1=CC(O)=CC2)C3=CC=C(C=C3)N4CCC(CN5CCN(CC5)C=6C=C7C(=CC6)C(=O)N(C7)[C@@H]8C(=O)NC(=O)CC8)CC4)C9=CC=C(C)C=C9

-20°C

51202000