PROTAC-O4I2

MedChem Express

PROTAC-O4I2

10

Research Use Only

99.66

C29H29ClN6O5S

609.10

PROTAC-O4I2 is a PROTAC targets splicing factor 3B1 ( SF3B1 ). PROTAC-O4I2 induces FLAG-SF3B1 degradation with an IC 50 value of 0.244 microM in K562 cells. PROTAC-O4I2 also induces cellular apoptosis in K562 WT cells [1] .

O=C(NCCCCCCNC1=CC=CC2=C1C(N(C2=O)C3CCC(NC3=O)=O)=O)C4=CSC(NC5=CC=C(C=C5)Cl)=N4

-20°C,2°C to 8°C

12352200