PROTAC SMARCA2 degrader-27

MedChem Express

PROTAC SMARCA2 degrader-27

9

Research Use Only

C58H71FN12O7

1067.26

PROTAC SMARCA2 degrader-27 (compound 4) is a PROTAC SMARCA2 degrader. PROTAC SMARCA2 degrader-27 has the potential to be used in cancer research (blue: SMARCA2 ligand, (HY-168232); black: linker, (HY-168231); pink: VHL ligand, (HY-168230))[1].

NC(N=N1)=C(N2CC3N(C4=CC(O[C@@H]5C[C@@H](OC6CCN(CC7CCN(C8=NOC([C@H](C(N9C[C@H](O)C[C@H]9C(N[C@H](C%10=CC(F)=C(C#N)C=C%10)C)=O)=O)C(C)C)=C8)CC7)CC6)C5)=NC=C4)C(CC3)C2)C=C1C%11=CC=CC=C%11O

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