PROTAC SMARCA2/4-degrader-10 [2568277-33-6]

TargetMol Chemicals

PROTAC SMARCA2/4-degrader-10 [2568277-33-6]

9

Research Use Only

C49H62N10O5S

903.15

PROTACSMARCA2/4-degrader-10 (compound I-399) is an effective SMARCA2 degrader with a DC50 value of less than 100 nM. It holds potential for use in cancer research.

NC1=C(C2=CN(N=C2)C3CCN(CC[C@@H]4CC[C@@H](C(N[C@H](C(=O)N5[C@H](C(NCC6=CC=C(C=C6)C7=C(C)N=CS7)=O)C[C@@H](O)C5)C(C)(C)C)=O)CC4)CC3)C=C(N=N1)C8=C(O)C=CC=C8

-20°C

51202000