PROTAC SOS1 degrader-8

MedChem Express

PROTAC SOS1 degrader-8

5

Research Use Only

C50H60ClN11O4

914.54

PROTAC SOS1 degrader-8 (Compd 1) is a PROTAC-based SOS1 degrader (Red: SOS1 Ligand (HY-161635), Black: linker (HY-W056267), Blue: E3 ligase ligand (HY-161637))[1].

N#CC1=C(C)C([C@@H](C)NC2=NN=C(C)C3=C2C=C(N4CCN(C(C5CCN(CC6CCC7(CCN(C(C8=CC(N9CCC(NC9=O)=O)=C(Cl)C=C8)=O)CC7)CC6)CC5)=O)CC4)N=C3)=CC=C1

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