PROTAC TYK2 degradation agent1 [2921556-14-9]

MedChem Express

PROTAC TYK2 degradation agent1 [2921556-14-9]

5

2921556-14-9

Research Use Only

99.50

C55H69N13O7S

1056.28

PROTAC TYK2 degradation agent1 is a potent and subtype-selective TYK2 degrader. PROTAC TYK2 degradation agent1 has TYK2 degradation activity with DC50 value of 14 nM. PROTAC TYK2 degradation agent1 can be used for the research of autoimmune disease[1].

CNC(C1=CN=C(C=C1NC2=C(C(C3=NN(C=N3)C)=CC=C2)OC)NC4=CC=C(C=N4)C(NCCCCCCCCCC(N[C@@H](C(C)(C)C)C(N5C[C@@H](C[C@H]5C(NCC6=CC=C(C=C6)C7=C(N=CS7)C)=O)O)=O)=O)=O)=O

-20°C

12131703