ProTAME

TargetMol Chemicals

ProTAME

65

1362911-19-0

Chemical

ProTAME

C34H38N4O12S

726.75

ProTAME is an inhibitor of APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, doxorubicin and etoposide, significantly increase cell death in primary cells and Multiple Myeloma (MM) cell lines, particularly if TOPIIalfa levels are first increased through pre-treatment with ProTAME.

3 years

S(N[C@@H](CCCN=C(NC(OCOC(CC1=CC=CC=C1)=O)=O)NC(OCOC(CC2=CC=CC=C2)=O)=O)C(OC)=O)(=O)(=O)C3=CC=C(C)C=C3

-20°

12352200