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Protein Tyrosine Phosphatase, non-receptor type 6(CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL [26628-22-8]

Protein Tyrosine Phosphatase, non-receptor type 6(CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL [26628-22-8]

BNC042259
Biotium
ReactivityBovine, Human, Mouse
Product group Antibodies
TargetPTPN6
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Overview

  • Supplier
    Biotium
  • Product Name
    Protein Tyrosine Phosphatase, non-receptor type 6(CPTC-PTPN6-2), CF405S conjugate, 0.1mg/mL
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    CPTC-PTPN6-2
  • Concentration
    0.1 mg/ml
  • Conjugate
    Other Conjugate
  • Gene ID5777
  • Target name
    PTPN6
  • Target description
    protein tyrosine phosphatase non-receptor type 6
  • Target synonyms
    HCP; HCPH; hematopoietic cell phosphatase; hematopoietic cell protein-tyrosine phosphatase; HPTP1C; protein-tyrosine phosphatase 1C; protein-tyrosine phosphatase SHP-1; PTP-1C; SHP1; SHP-1; SHP-1L; SH-PTP1; tyrosine-protein phosphatase non-receptor type 6
  • Host
    Mouse
  • Isotype
    IgG2a
  • Protein IDP29350
  • Protein Name
    Tyrosine-protein phosphatase non-receptor type 6
  • Scientific Description
    PTPN6, which is also designated as SHP-1, is expressed primarily in hematopoietic cells and characterized by the presence of two SH2 domains N-terminal to the PTP domain. It maps to 12p13, a region commonly involved in leukemia-associated chromosomal abnormalities. SHP-1 plays a role in modulating intracellular signaling for various molecules. In T-cell lymphomas and other malignancies, SHP-1 phosphatase expression is lost, by a thus far undetermined mechanism. Preliminary studies suggest that it may be helpful in differentiating mantle/marginal zone lymphomas (SHP-1 ) from follicular lymphomas (SHP-1 negative). Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
  • Source
    Animal
  • Reactivity
    Bovine, Human, Mouse
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203