CD275 [B7-H2] (mouse):Fc (mouse) (rec.)

Chimerigen Laboratories

CD275 [B7-H2] (mouse):Fc (mouse) (rec.)

10

Research Use Only

>98%

Mouse B7-H2, also called CD275, B7RP-1, B7h, LICOS and GL50, is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation. - Protein. The extracellular domain of mouse CD275 [B7-H2] (aa 48-279) is fused to the N-terminus of the Fc region of mouse IgG2a. Source: CHO cells. Endotoxin content: <0.06EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Mouse B7-H2, also called CD275, B7RP-1, B7h, LICOS and GL50, is a member of the growing B7 family of immune costimulatory proteins. CD275 has been identified as the ligand for ICOS, a member of the CD28 family of co-stimulatory receptors. Mouse CD275 is expressed on resting B cells and at low levels on monocytes. The CD275/ ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

-20°C,2°C to 8°C

12352202