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Flagellin (NLRC4 Mutant) (rec.)

Catalog number: AG-40B-0126-C010
Brand: AdipoGen Life Sciences
Packing: 10 ug
Other sizes: Other size available
Price: € 200.00
Expected delivery time: 7 days
Quantity:
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Product specifications for - Flagellin (NLRC4 Mutant) (rec.)

Overview: 
Product group: Proteins / Signaling Molecule
Category: Proteins
Properties: 
Purity: >95% (SDS-PAGE)
Datasheet: Datasheet
  Research Use Only
UNSPSC: 12352202
Concentration: 0.1 mg/ml
Form supplied: Lyophilized. Contains PBS.
Storage instructions: 2-¦C to 8-¦C, -20-¦C
Scientific information: 
Scientific info: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (NLRC4 Mutant)(rec.) is only detected by TLR5 not by NLRC4. - Protein. The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) contains a small deletion at the C-terminus of the protein required for NLRC4 activation and is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Detected by human and mouse TLR5 (Toll-like receptor 5). Not detected by mouse NLRC4 (Nod-like receptor [NLR] family caspase activation and recruitment domain [CARD] domain-containing protein 4). Purity: >95% (SDS-PAGE). Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (NLRC4 Mutant)(rec.) is only detected by TLR5 not by NLRC4.
Safety information: 
MSDS: MSDS
Hazard information: Non-hazardous
Additional information: 
Synonyms: AG-40B-0126-C010; AdipoGen Life Sciences