Flagellin (rec.) (AG-40B-0125) and Flagellin (NLRC4 Mutant) (rec.) (AG-40B-0126) induce CCL20-luciferase promoter through TLR5 in vitro. Method: Caco-2 cells transfected with plasmid encoding CCL20-LUC plasmid are activated for 24h wit
Flagellin (rec.) (AG-40B-0125) and Flagellin (NLRC4 Mutant) (rec.) (AG-40B-0126) induce CCL20-luciferase promoter through TLR5 in vitro. Method: Caco-2 cells transfected with plasmid encoding CCL20-LUC plasmid are activated for 24h wit
Flagellin (TLR5 Mutant) (rec.)
AG-40B-0127
Product group Proteins / Signaling Molecules
Overview
- SupplierAdipoGen Life Sciences
- Product NameFlagellin (TLR5 Mutant) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Concentration0.1 mg/ml
- Estimated Purity>95%
- Scientific DescriptionFlagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (TLR5 Mutant) (rec.) cannot be detected by human and mouse TLR5. It has not been tested on NLRC4. - Protein. The native flagellin [FliC] from Salmonella enterica Serovar Typhimurium strain ATCC14028 (aa 1-495) contains a substitution of amino acids 90-97 required for TLR5 signaling by a motif from a non-signaling flagellin and is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Not detected by human and mouse TLR5 (Toll-like receptor 5). Purity: >95% (SDS-PAGE). Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (TLR5 Mutant) (rec.) cannot be detected by human and mouse TLR5. It has not been tested on NLRC4.
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352202