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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
IL-10 (human):Fc (human) (rec.) (non-lytic)
Catalog number:
CHI-HF-22010-C050
Brand:
Chimerigen Laboratories
Packing:
50 ug
Other sizes:
Other sizes available
Price:
€ 375.00
Expected delivery time:
7 days
Quantity:
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General
References
Product specifications for - IL-10 (human):Fc (human) (rec.) (non-lytic)
Overview:
Product group:
Proteins / Signaling Molecule
Category:
Chemokines / cytokines
Species:
Human
Properties:
Purity:
>98% (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352202
Form supplied:
Lyophilized from 0.2um-filtered solution in PBS.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases. - Protein. The extracellular domain of human IL-10 (aa 19-178) is fused to the N-terminus of the Fc region of a mutant human IgG1. Source: CHO cells. Endotoxin content: <0.06EU/microg protein (LAL test; Lonza). Lyophilized from 0.2microm-filtered solution in PBS. Purity: >98% (SDS-PAGE). Interleukin-10 (IL-10) is a cytokine produced by activated Th2 cells, B cells, keratinocytes and monocytes/macrophages. In vitro murine and human IL-10 inhibits cytokine synthesis by Th1 cells, natural killer cells and monocytes/macrophages. Several studies have suggested the potential application of IL-10 as an anti-inflammatory agent in the treatment of septic shock and as an immunosuppressive agent in certain T cell mediated autoimmune diseases.
Safety information:
Hazard information:
Non-hazardous
Additional information:
Synonyms:
CHI-HF-22010-C050; Chimerigen Laboratories
Administration of noncytolytic IL-10/Fc in murine models of lipopolysaccharide-induced septic shock and allogeneic islet transplantation: X.X. Zheng, et al.; J. Immunol. 154, 5590 (1995)
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