IL-1R1 (human):Fc (human) (... | AG-40B-0024-C050 | AdipoGen - Bio-Connect

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Description
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General

Product specifications for - IL-1R1 (human):Fc (human) (rec.)

Overview:
Product group:	Proteins / Signaling Molecule
Category:	Chemokines / cytokines
Species:	Human
Target:	IL1R1
Target description:	interleukin 1 receptor type 1

Properties:
Purity:	>95% (SDS-PAGE)
Molecular weight:	~80kDa (SDS-PAGE)
Datasheet:	Datasheet
	Research Use Only
UNSPSC:	12352202
Concentration:	1 mg/ml
Form supplied:	Lyophilized. Contains PBS.
Storage instructions:	2-¦C to 8-¦C, -20-¦C

Scientific information:
Scientific info:	IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2. - Protein. Human IL-1RI (interleukin-1 receptor type I) (aa 21-336) is fused at the C-terminus to the Fc portion of human IgG1. Source: HEK 293 cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human IL-1beta. Purity: >95% (SDS-PAGE). IL-1RI is the receptor for interleukin-1alpha (IL-1A), beta (IL-1B) and interleukin-1 receptor antagonist protein (IL-1RA). Binding to the agonist leads to the activation of NF-kappaB. Signaling involves formation of a ternary complex containing IL1RAP, leading the activation of TOLLIP, MYD88 and IRAK1 or IRAK2.
Gene ID:	3554
Swiss prot ID:	P14778

Safety information:
MSDS:	MSDS
Hazard information:	Non-hazardous

Additional information:
Synonyms:	AG-40B-0024-C050; AdipoGen Life Sciences; CD121 antigen-like family member A; CD121A; D2S1473; IL1R; IL-1R-1; IL1RA; IL-1R-alpha; IL-1RT1; IL-1RT-1; interleukin 1 receptor alpha, type I; interleukin-1 receptor alpha; interleukin-1 receptor type 1; interleukin-1 receptor type I; P80