IL-6R alpha Protein, Human (CHO)
HY-P7223
Overview
- SupplierMedChem Express
- Product NameIL-6R alpha Protein, Human (CHO)
- Delivery Days Customer10
- Protein IDP08887
- Protein NameInterleukin-6 receptor subunit alpha
- Scientific DescriptionIL-6R alpha is a subunit alpha of IL-6 receptors, also shared by other interleukin receptors. IL-6R alpha acts as IL-6 agonist and involves in JAK/STAT, MAPK, and Akt signaling pathway. IL-6R alpha/CD126, Human consists of 468 amino acids (M1-R468) with two fibronectin type-III-like domains contained in the N-terminal part (113-217 a.a, 218-316 a.a), and a soluble form (1-365 a.a). Soluble IL-6R (sIL-6R) binds IL-6 and dimerized gp130 to achieve trans signaling, and exhibits a tissue expression property in some immune systems. IL-6R alpha Protein, Human (L20-P365) is soluble form and expressed by CHO cells with a full length of the sequence of 346 amino acids.
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352202