Jagged-1 (mouse):Fc (human) (rec.)
![Research Use Only](static/images/certificates/ruo.jpg)
AG-40A-0157T
Overview
- SupplierAdipoGen Life Sciences
- Product NameJagged-1 (mouse):Fc (human) (rec.)
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity>90%
- Protein IDQ9QXX0
- Protein NameProtein jagged-1
- Scientific DescriptionJagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF). - Protein. Signal peptide and extracellular domain of mouse Jagged-1 (aa 1-1067) are fused at the C-terminus to the Fc portion of human IgG. Source: HEK 293 cells. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >90% (SDS-PAGE). Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is involved in early and late stages of mammalian cardiovascular development. Inhibits myoblast differentiation. Enhances fibroblast growth factor-induced angiogenesis (in vitro). Defects in Jagged-1 are the cause of Alagille syndrome type 1 (ALGS1) and tetralogy of Fallot (TOF).
- Storage Instruction2°C to 8°C,-20°C
- UNSPSC12352202