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Binding of LAG-3 (human):Fc (human) (rec.) (Prod. No. AG-40B-0031) on dendritic and B cells. Method: Monocyte-derived immature DC (iDC), DC matured for 48h with LPS (mDC) and EBV-transformed B-cells are incubated with either an anti-
Binding of LAG-3 (human):Fc (human) (rec.) (Prod. No. AG-40B-0031) on dendritic and B cells. Method: Monocyte-derived immature DC (iDC), DC matured for 48h with LPS (mDC) and EBV-transformed B-cells are incubated with either an anti-
Binding of LAG-3 (human):Fc (human) (rec.) (Prod. No. AG-40B-0031) on dendritic and B cells. Method: Monocyte-derived immature DC (iDC), DC matured for 48h with LPS (mDC) and EBV-transformed B-cells are incubated with either an anti-

LAG-3 (human):Fc (human) (rec.)

Research Use Only
AG-40B-0031
AdipoGen Life Sciences
Protein IDP18627
Product group Proteins / Signaling Molecules
Price on request
Packing Size
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Overview

  • Supplier
    AdipoGen Life Sciences
  • Product Name
    LAG-3 (human):Fc (human) (rec.)
  • Delivery Days Customer
    10
  • Certification
    Research Use Only
  • Concentration
    0.5 mg/ml
  • Estimated Purity
    >99%
  • Protein IDP18627
  • Protein Name
    Lymphocyte activation gene 3 protein
  • Scientific Description
    Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. - Protein. The sequence coding for the 4 extracellular Ig-like domains of human LAG-3 (D1-D4) is fused to the Fc portion of human IgG1. Source: CHO cells. Endotoxin content: <0.1EU/microg purified protein (LAL test; Lonza). Liquid. In PBS. Binds to human, mouse and monkey MHC class II. Purity: >99% (SDS-PAGE). Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
  • Storage Instruction
    2°C to 8°C,-20°C
  • UNSPSC
    12352202