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Description
Catalog number
CAS No.
Clone ID
News
Vorige
Volgende
TNF-alpha, Soluble (human) (rec.)
Catalog number:
AG-40B-0006-C010
Brand:
AdipoGen Life Sciences
Packing:
10 ug
Other sizes:
Other sizes available
Price:
€ 90.00
Expected delivery time:
7 days
Quantity:
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General
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Product specifications for - TNF-alpha, Soluble (human) (rec.)
Overview:
Product group:
Proteins / Signaling Molecule
Category:
Proteins
Species:
Human, Mouse
Target:
TNF
Target description:
tumor necrosis factor
Properties:
Purity:
>95% (SDS-PAGE)
Molecular weight:
~17kDa (SDS-PAGE)
Datasheet:
Datasheet
Research Use Only
UNSPSC:
12352202
Form supplied:
Lyophilized. Contains PBS.
Storage instructions:
2-¦C to 8-¦C, -20-¦C
Scientific information:
Scientific info:
Protein. A FLAG®-tag is fused at the N-terminus of human TNF-alpha (aa 85-223). Source: E. coli. Endotoxin content: <0.01EU/microg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Binds to human and mouse TNF-R1. Purity: >95% (SDS-PAGE). Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (MultimericTNF-alpha (Prod. No. AG-40B-0019). Since the MultimericTNF-alpha mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either normal TNF-alpha or MultimericTNF-alpha can be used. - Tumor necrosis factor (TNF, cachexin or cachectin and formerly known as tumor necrosis factor-alpha) is a cytokine involved in systemic inflammation and is a member of a group of cytokines that stimulate the acute phase reaction. The receptor TNF-R1 is activated by both the membrane-bound and soluble trimeric forms of TNF-alpha, whereas the receptor TNF-R2 only responds to the membrane-bound form of TNF-alpha (MultimericTNF-alpha (Prod. No. AG-40B-0019). Since the MultimericTNF-alpha mimics the membrane-bound form (forms oligomers higher than trimer), it is the only TNF-alpha protein that can activate the TNF-R2. For TNF-R1 activation, either normal TNF-alpha or MultimericTNF-alpha can be used.
Gene ID:
7124
Swiss prot ID:
P01375
Safety information:
MSDS:
MSDS
Hazard information:
Non-hazardous
Additional information:
Synonyms:
AG-40B-0006-C010; AdipoGen Life Sciences; APC1 protein; cachectin; DIF; TNF, macrophage-derived; TNF, monocyte-derived; TNF-a; TNFA; TNF-alpha; TNFSF2; TNLG1F; tumor necrosis factor; tumor necrosis factor ligand 1F; tumor necrosis factor ligand superfamily member 2; tumor necrosis factor-alpha